A small-molecule SUMOylation inhibitor activates antitumor immune responses and potentiates immune therapies in preclinical models.
Lightcap ES, Yu P, Grossman S, Song K, Khattar M, Xega K, He X, Gavin JM, Imaichi H, Garnsey JJ, Koenig E, Zhang H, Lu Z, Shah P, Fu Y, Milhollen MA, Hatton BA, Riceberg J, Shinde V, Li C, Minissale J, Yang X, England D, Klinghoffer RA, Langston S, Galvin K, Shapiro G, Pulukuri SM, Fuchs SY, Huszar D.. Pharmeur Sci Notes. 2006 Dec;2006(2):53-4. Pharmeur Sci Notes. 2006. PMID: 17691216
.
Griffin ME, et al. Science. 2021 Aug 27;373(6558):1040-1046. doi: 10.1126/science.abc9113. Science. 2021. PMID: 34446607.