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Ketamine and other glutamate receptor modulators for depression in adults with unipolar major depressive disorder.
Dean RL, Hurducas C, Hawton K, Spyridi S, Cowen PJ, Hollingsworth S, Marquardt T, Barnes A, Smith R, McShane R, Turner EH, Cipriani A.. Bar-On YM, et al. N Engl J Med. 2021 Sep 15. doi: 10.1056/NEJMoa2114255. Online ahead of print. N Engl J Med. 2021. PMID: 34525275.
FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Goold R, Hamilton J, Menneteau T, Flower M, Bunting EL, Aldous SG, Porro A, Vicente JR, Allen ND, Wilkinson H, Bates GP, Sartori AA, Thalassinos K, Balmus G, Tabrizi SJ.. Griffin ME, et al. Science. 2021 Aug 27;373(6558):1040-1046. doi: 10.1126/science.abc9113. Science. 2021. PMID: 34446607.
USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3.
Cai B, Zhao J, Zhang Y, Liu Y, Ma C, Yi F, Zheng Y, Zhang L, Chen T, Liu H, Liu B, Gao C.

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